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Frequently asked questions

How does a serological test work?

The test works by detecting allergen-specific antibodies in the blood. The antibodies sought are specific IgE immunoglobulins.

IgE serological tests have no value in food allergy.

Adverse reactions to food are often mediated by IgE, but not always. Some may be caused by other hypersensitivity mechanisms (type IV for example) and by intolerance phenomena leading to a cascade of clinical events.

That is why, in case of suspicion of food allergy, proper analysis must first determine whether or not IgE is involved and only then can a suitable diet be chosen. The success of the diet, i.e. improvement of clinical signs, will determine the diagnosis definitively.

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What are the benefits of a serological test?

EASY - Each test requires only a small amount of blood (1 mL).

FAST - Results are available within 15 days.

SIMPLE – Our laboratory performs the analysis and provides the results in an easily understandable form.

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Why prescribe Galileo Diagnostics tests?

Galileo Diagnostics through its parent company Genclis has 10 years of experience of allergy serological tests. Thousands of samples have been analysed with results leading to dietary management and other actions improving clinical symptoms. Specialising in cloning protein antigens, Genclis is a pioneer in Component-Resolved Diagnosis (CRD) for diagnosis improved by the knowledge of certain highly targeted allergen components, thereby demonstrating that allergy serological tests continue to make great advances in technology. In veterinary medicine, the SENSITEST® range is recognised as a diagnostic tool and the Cyno-DIAL® and Feli-DIAL® tests are true innovations offering, for the first time, guidance in deciding the best choice of food.

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How do I manage the symptoms of atopic dermatitis?

Management of complications:

In most cases, infectious complications due to bacteria and fungi will develop. Diagnosis is made with simple tests. Treatment is based on antibiotics, antifungals and shampoos.

Elimination of fleas:

Treatment is essential even if fleas are not visible. Flea bites on sensitive skin create very severe skin reactions.

Treatment is renewed every month, all year long.

Management of pruritus:

The most problematic symptom of atopic dermatitis is that your pet scratches. Itching is managed by:

  • Treatment of complications
  • Administration of oral or topical medication to sooth itching
  • Cleaning and maintenance of the skin
  • Elimination of allergy causes (exposure to certain allergens and elimination of certain foods on a case-by-case basis and if possible)

Restructuring the skin barrier:

  • Regular bathing with mild shampoos at least once per week
  • Application of emollients (moisturisers) every day or at the very least after every shampoo

Management of causes:

  • Implementation of an elimination diet
  • Search for other causes of allergy and desensitisation (immunotherapy)
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What are the treatments available for my animal for allergic atopic dermatitis?

This skin disease is influenced by a genetic component that makes your animal develop allergies throughout its life.

Current treatments aim to reduce the frequency and intensity of attacks in order to provide a more comfortable life for the animal.

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If I want to implement immunotherapy following the results of SENSITEST®, should I choose all allergens to which the animal is sensitised?

If the animal shows several sensitisations, this may be due to a “cross reaction”. The same substances are present in several extracts with similar sources (e.g. several species of mites or pollen) explaining the various positive results.

Good knowledge of molecular allergology, support of pollen calendars and clinical observations can help target the substances to select.

We recommend, for example, visiting the website www.rnsa.fr (for France) to check if there is any consistency between symptoms and exposure to pollen (please return to your country website that is dedicated to monitoring pollen exposure).

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In SENSITEST®, do the allergen sensitisation scores correlate with the intensity of symptoms observed?

The sensitisation score is not proportional to the intensity of the observed clinical signs. From low sensitisation (score 1), clinical signs of allergy can be significant.

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When implementing an elimination diet, can I give the animal treats exceptionally?

The elimination diet must be followed strictly. Treats, even given in very small quantities, can lead to reappearance of food allergy symptoms.

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Is Feli-DIAL® able to diagnose food allergy in cats?

Feli-DIAL® is not a diagnostic test for food allergy. At present, only an elimination diet and rigorously conducted reintroduction allows diagnosis.

Feli-DIAL® helps decide the best choice of food to be used in the implementation of the food elimination diet. It reveals food to which the cat is not sensitised and thus avoids multiple food tests before finding the right food. It saves time when managing the allergy and improves the animal’s comfort.

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Should I stop symptomatic treatments before taking a sample for Cyno-DIAL®, Feli-DIAL® or SENSITEST®?

Symptomatic treatments interfere little in serological tests for the dosage and search for specific IgE, a category of tests which includes Cyno-DIAL®, Feli-DIAL® and SENSITEST®.

Short-acting oral glucocorticoids – The few studies in dogs have concluded that their administration over a period of less than two months has no effect on specific IgE. In cats, one study has described the lack of effect of one month of treatment on specific IgE.

Injectable long-acting glucocorticoids – Few studies exist on the effect on specific IgE in dogs and cats. It seems that treatment lasting for 28 days does not alter the dosage results or the search for specific IgE.

Topical glucocorticoids - Like oral steroids, it is reasonable to assume that topical corticosteroids also do not affect the dosage and search for specific IgE.

The effect of antihistamines has not been studied in dogs and cats. However, the mechanism of action of these molecules is known and should not, in theory, interfere with the dosage and search for specific IgE.

Studies in which cyclosporin was used for a period of up to two months to treat canine atopic dermatitis concluded that the molecule has no effect on specific IgE.

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How do I prepare my sample?

Collect venous blood in a dry tube or another tube allowing coagulation.

Allow it to clot at room temperature for at least 30 minutes.

Centrifuge the tube at room temperature.

Collect the serum and transfer it to the supplied transport tube (1 tube per test containing 1 mL minimum of serum).

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